Recombinant Human ARHGDIB, GST-tagged
Cat.No. : | ARHGDIB-9829H |
Product Overview : | Recombinant Human ARHGDIB protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]). |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-201a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ARHGDIB Rho GDP dissociation inhibitor (GDI) beta [ Homo sapiens ] |
Official Symbol : | ARHGDIB |
Synonyms : | ARHGDIB; Rho GDP dissociation inhibitor (GDI) beta; GDIA2, GDID4, RAP1GN1; rho GDP-dissociation inhibitor 2; Ly GDI; RhoGDI2; Rho GDI 2; rho-GDI beta; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; |
Gene ID : | 397 |
mRNA Refseq : | NM_001175 |
Protein Refseq : | NP_001166 |
MIM : | 602843 |
UniProt ID : | P52566 |
Chromosome Location : | 12p12.3 |
Pathway : | Caspase cascade in apoptosis, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; |
Function : | GTPase activator activity; Rho GDP-dissociation inhibitor activity; |
Products Types
◆ Recombinant Protein | ||
ARHGDIB-689M | Recombinant Mouse ARHGDIB Protein, His (Fc)-Avi-tagged | +Inquiry |
Arhgdib-646M | Recombinant Mouse Arhgdib Protein, MYC/DDK-tagged | +Inquiry |
ARHGDIB-374H | Recombinant Human ARHGDIB Protein, His (Fc)-Avi-tagged | +Inquiry |
ARHGDIB-3500H | Recombinant Human ARHGDIB protein, His-tagged | +Inquiry |
ARHGDIB-775H | Recombinant Human ARHGDIB protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ARHGDIB-8735HCL | Recombinant Human ARHGDIB 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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