Recombinant Human ATG10, GST-tagged ATG10-9968H

Recombinant Human ATG10, GST-tagged


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Recombinant Human ATG10, GST-tagged

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Cat.No. : ATG10-9968H
Product Overview : Recombinant Human ATG10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-220a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : ATG10 ATG10 autophagy related 10 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : ATG10
Synonyms : ATG10; ATG10 autophagy related 10 homolog (S. cerevisiae); APG10 autophagy 10 like (S. cerevisiae) , APG10L; ubiquitin-like-conjugating enzyme ATG10; DKFZP586I0418; FLJ13954; autophagy-related protein 10; APG10; APG10L; pp12616; DKFZp586I0418;
Gene ID : 83734
mRNA Refseq : NM_001131028
Protein Refseq : NP_001124500
MIM : 610800
UniProt ID : Q9H0Y0
Chromosome Location : 5q14.1
Pathway : Senescence and Autophagy, organism-specific biosystem;
Function : Atg12 ligase activity; ligase activity;

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