Recombinant Human B2M, GST-tagged

Cat.No.: B2M-10092H
Product Overview: Recombinant Human B2M protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Source: E.coli
Species: Human
Tag: GST
Protein length: 22-119a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: B2M beta-2-microglobulin [ Homo sapiens ]
Official Symbol: B2M
Synonyms: B2M; beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules;
Gene ID: 567
mRNA Refseq: NM_004048
Protein Refseq: NP_004039
MIM: 109700
UniProt ID: P61769
Chromosome Location: 15q21-q22.2
Pathway: Adaptive Immune System, organism-specific biosystem; Amyloids, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing &
Function: protein binding;

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