"BEST3" Related Products

Recombinant Human BEST3, His-tagged

Cat.No.: BEST3-10209H
Product Overview: Recombinant Human BEST3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).
Source: E.coli
Species: Human
Tag: His
Protein length: C-term-186a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: BEST3 bestrophin 3 [ Homo sapiens ]
Official Symbol: BEST3
Synonyms: BEST3; bestrophin 3; vitelliform macular dystrophy 2 like 3 , VMD2L3; bestrophin-3; MGC13168; MGC40411; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; VMD2L3;
Gene ID: 144453
mRNA Refseq: NM_032735
Protein Refseq: NP_116124
MIM: 607337
UniProt ID: Q8N1M1
Chromosome Location: 12q14.2-q15
Function: chloride channel activity; ion channel activity; molecular_function;

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