Recombinant Human BEST3, His-tagged
Cat.No. : | BEST3-10209H |
Product Overview : | Recombinant Human BEST3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | C-term-186a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | BEST3 bestrophin 3 [ Homo sapiens ] |
Official Symbol : | BEST3 |
Synonyms : | BEST3; bestrophin 3; vitelliform macular dystrophy 2 like 3 , VMD2L3; bestrophin-3; MGC13168; MGC40411; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; VMD2L3; |
Gene ID : | 144453 |
mRNA Refseq : | NM_032735 |
Protein Refseq : | NP_116124 |
MIM : | 607337 |
UniProt ID : | Q8N1M1 |
Chromosome Location : | 12q14.2-q15 |
Function : | chloride channel activity; ion channel activity; molecular_function; |
Products Types
◆ Recombinant Protein | ||
Best3-313M | Recombinant Mouse Best3 Protein, His&GST-tagged | +Inquiry |
Best3-1860M | Recombinant Mouse Best3 Protein, Myc/DDK-tagged | +Inquiry |
BEST3-1014M | Recombinant Mouse BEST3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BEST3-4453C | Recombinant Chicken BEST3 | +Inquiry |
BEST3-2378M | Recombinant Mouse BEST3 Protein | +Inquiry |
◆ Lysates | ||
BEST3-8466HCL | Recombinant Human BEST3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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