Recombinant Human BEST4, His-tagged BEST4-10210H

Recombinant Human BEST4, His-tagged


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Recombinant Human BEST4, His-tagged

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Cat.No. : BEST4-10210H
Product Overview : Recombinant Human BEST4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3 ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
Source : E.coli
Species : Human
Tag : His
Protein length : 95-473a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : BEST4 bestrophin 4 [ Homo sapiens ]
Official Symbol : BEST4
Synonyms : BEST4; bestrophin 4; vitelliform macular dystrophy 2 like 2 , VMD2L2; bestrophin-4; vitelliform macular dystrophy 2-like 2; vitelliform macular dystrophy 2-like protein 2; VMD2L2; MGC126872;
Gene ID : 266675
mRNA Refseq : NM_153274
Protein Refseq : NP_695006
MIM : 607336
UniProt ID : Q8NFU0
Chromosome Location : 1p33-p32.3
Function : chloride channel activity; ion channel activity; molecular_function;

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