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Recombinant Human CD180, His-tagged

Cat.No.: CD180-10915H
Product Overview: Recombinant Human CD180 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10.
Source: E.coli
Species: Human
Tag: His
Protein length: C-term-348a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: CD180 CD180 molecule [ Homo sapiens ]
Official Symbol: CD180
Synonyms: CD180; CD180 molecule; CD180 antigen , LY64, lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD; CD180 antigen; Ly78; RP105; lymphocyte antigen 64; radioprotective 105 kDa protein; lymphocyte antigen-64, radioprotective, 105kDa; LY64; MGC126233; MGC126234;
Gene ID: 4064
mRNA Refseq: NM_005582
Protein Refseq: NP_005573
MIM: 602226
UniProt ID: Q99467
Chromosome Location: 5q12
Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Toll Like Receptor 4 (TLR4) Cascade, organism-specific biosystem; Toll Receptor Cascades, organism-specific biosystem;
Function: receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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