Recombinant Human CERK, GST-tagged

• Cat.No.: CERK-11123H
• Product Overview: Recombinant Human CERK protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-201
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CERK ceramide kinase [ Homo sapiens ]
• Official Symbol: CERK
• Synonyms: CERK; ceramide kinase; dA59H18.2; dA59H18.3; DKFZp434E0211; FLJ21430; FLJ23239; hCERK; KIAA1646; LK4; lipid kinase 4; lipid kinase LK4; acylsphingosine kinase; MGC131878
• Gene ID: 64781
• mRNA Refseq: NM_022766
• Protein Refseq: NP_073603
• MIM: 610307
• UniProt ID: Q8TCT0
• Chromosome Location: 22q13.31
• Pathway: Glycosphingolipid metabolism, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, conserved biosystem
• Function: ATP binding; ceramide kinase activity; diacylglycerol kinase activity; magnesium ion binding; nucleotide binding; transferase activity