"CHMP1B" Related Products

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Recombinant Human CHMP1B, GST-tagged

Cat.No.: CHMP1B-11183H
Product Overview: Recombinant Human CHMP1B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-199a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: CHMP1B charged multivesicular body protein 1B [ Homo sapiens ]
Official Symbol: CHMP1B
Synonyms: CHMP1B; charged multivesicular body protein 1B; chromatin modifying protein 1B; charged multivesicular body protein 1b; C18orf2; CHMP1.5; Vps46B; vacuolar protein sorting 46-2; chromatin-modifying protein 1b; vacuolar protein sorting-associated protein 46-2; C10orf2; Vps46-2; C18-ORF2; hVps46-2;
Gene ID: 57132
mRNA Refseq: NM_020412
Protein Refseq: NP_065145
MIM: 606486
UniProt ID: Q7LBR1
Chromosome Location: 18p11.21
Pathway: ESCRT-III complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem;
Function: protein binding; protein domain specific binding;

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