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Recombinant Human CKM, His-tagged

Cat.No.: CKM-11265H
Product Overview: Recombinant Human CKM protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-381a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: CKM creatine kinase, muscle [ Homo sapiens ]
Official Symbol: CKM
Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK;
Gene ID: 1158
mRNA Refseq: NM_001824
Protein Refseq: NP_001815
MIM: 123310
UniProt ID: P06732
Chromosome Location: 19q13.32
Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Creatine pathway, organism-specific biosystem; Creatine pathway, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function: ATP binding; creatine kinase activity; nucleotide binding;

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