Recombinant Human COL25A1, His-tagged
Cat.No. : | COL25A1-11430H |
Product Overview : | Recombinant Human COL25A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | C-term-332a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | COL25A1 collagen, type XXV, alpha 1 [ Homo sapiens ] |
Official Symbol : | COL25A1 |
Synonyms : | COL25A1; collagen, type XXV, alpha 1; collagen alpha-1(XXV) chain; alzheimer disease amyloid-associated protein; collagenous Alzheimer amyloid plaque component; collagen-like Alzheimer amyloid plaque component; AMY; CLAC; CLACP; CLAC-P; |
Gene ID : | 84570 |
mRNA Refseq : | NM_001256074 |
Protein Refseq : | NP_001243003 |
MIM : | 610004 |
UniProt ID : | Q9BXS0 |
Chromosome Location : | 4q25 |
Function : | beta-amyloid binding; heparin binding; |
Products Types
◆ Recombinant Protein | ||
COL25A1-1644H | Recombinant Human COL25A1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
COL25A1-7377HCL | Recombinant Human COL25A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All COL25A1 Products
Required fields are marked with *
My Review for All COL25A1 Products
Required fields are marked with *
0
Inquiry Basket