Recombinant Human COX17, GST-tagged
Cat.No. : | COX17-11488H |
Product Overview : | Recombinant Human COX17 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-63a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | COX17 |
Synonyms : | COX17; COX17 cytochrome c oxidase assembly homolog (S. cerevisiae); COX17 (yeast) homolog, cytochrome c oxidase assembly protein , COX17 homolog, cytochrome c oxidase assembly protein (S. cerevisiae) , COX17 homolog, cytochrome c oxidase assembly protein (yeast); cytochrome c oxidase copper chaperone; human homolog of yeast mitochondrial copper recruitment; MGC104397; MGC117386; |
Gene ID : | 10063 |
mRNA Refseq : | NM_005694 |
Protein Refseq : | NP_005685 |
MIM : | 604813 |
UniProt ID : | Q14061 |
Chromosome Location : | 3q13.33 |
Pathway : | Cytochrome c oxidase, organism-specific biosystem; Cytochrome c oxidase, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem; Oxidative phosphorylation, organism-specific biosystem; |
Function : | copper chaperone activity; copper ion binding; enzyme activator activity; metal ion binding; |
Products Types
◆ Recombinant Protein | ||
COX17-809R | Recombinant Rhesus Macaque COX17 Protein, His (Fc)-Avi-tagged | +Inquiry |
COX17-1738H | Recombinant Human COX17 Protein, GST-tagged | +Inquiry |
COX17-1911M | Recombinant Mouse COX17 Protein, His (Fc)-Avi-tagged | +Inquiry |
COX17-1366Z | Recombinant Zebrafish COX17 | +Inquiry |
COX17-984R | Recombinant Rhesus monkey COX17 Protein, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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