Recombinant Human CPSF3, GST-tagged CPSF3-11537H

Recombinant Human CPSF3, GST-tagged

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Recombinant Human CPSF3, GST-tagged

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Cat.No. : CPSF3-11537H
Product Overview : Recombinant Human CPSF3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3-end pre-mRNA processing.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-348a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CPSF3 cleavage and polyadenylation specific factor 3, 73kDa [ Homo sapiens ]
Official Symbol : CPSF3
Synonyms : CPSF3; cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specific factor 3, 73kD subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF 73; CPSF73; YSH1; CPSF 73 kDa subunit; mRNA 3-end-processing endonuclease CPSF-73; cleavage and polyadenylation specificity factor 3; cleavage and polyadenylation specificity factor 73 kDa subunit; CPSF; CPSF-73;
Gene ID : 51692
mRNA Refseq : NM_016207
Protein Refseq : NP_057291
MIM : 606029
UniProt ID : Q9UKF6
Chromosome Location : 2p25.1
Pathway : Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Processing of Capped Intronless Pre-mRNA, organism-specific biosystem; Processing of Intronless Pre-mRNAs, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem; RNA Polymerase II Transcription Termination, organism-specific biosystem;
Function : 5-3 exonuclease activity; RNA binding; endoribonuclease activity; hydrolase activity; metal ion binding; protein binding;

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