Recombinant Human CPSF3, GST-tagged
Cat.No. : | CPSF3-11537H |
Product Overview : | Recombinant Human CPSF3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3-end pre-mRNA processing. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-348a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CPSF3 cleavage and polyadenylation specific factor 3, 73kDa [ Homo sapiens ] |
Official Symbol : | CPSF3 |
Synonyms : | CPSF3; cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specific factor 3, 73kD subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF 73; CPSF73; YSH1; CPSF 73 kDa subunit; mRNA 3-end-processing endonuclease CPSF-73; cleavage and polyadenylation specificity factor 3; cleavage and polyadenylation specificity factor 73 kDa subunit; CPSF; CPSF-73; |
Gene ID : | 51692 |
mRNA Refseq : | NM_016207 |
Protein Refseq : | NP_057291 |
MIM : | 606029 |
UniProt ID : | Q9UKF6 |
Chromosome Location : | 2p25.1 |
Pathway : | Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Processing of Capped Intronless Pre-mRNA, organism-specific biosystem; Processing of Intronless Pre-mRNAs, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem; RNA Polymerase II Transcription Termination, organism-specific biosystem; |
Function : | 5-3 exonuclease activity; RNA binding; endoribonuclease activity; hydrolase activity; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
CPSF3-655H | Recombinant Human CPSF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CPSF3-1812H | Recombinant Human CPSF3 Protein, GST-tagged | +Inquiry |
CPSF3-1127Z | Recombinant Zebrafish CPSF3 | +Inquiry |
◆ Lysates | ||
CPSF3-7304HCL | Recombinant Human CPSF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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