Recombinant Human CTSD, GST-tagged

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Recombinant Human CTSD, GST-tagged

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Cat.No. : CTSD-11684H
Product Overview : Recombinant Human CTSD protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-354a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CTSD cathepsin D [ Homo sapiens ]
Official Symbol : CTSD
Synonyms : CTSD; cathepsin D; cathepsin D (lysosomal aspartyl protease) , CPSD; ceroid lipofuscinosis; neuronal 10; CLN10; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; CPSD; MGC2311;
Gene ID : 1509
mRNA Refseq : NM_001909
Protein Refseq : NP_001900
MIM : 116840
UniProt ID : P07339
Chromosome Location : 11p15.5
Pathway : Ceramide signaling pathway, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Function : aspartic-type endopeptidase activity; peptidase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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