Recombinant Human CYB5A, GST-tagged

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Recombinant Human CYB5A, GST-tagged

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Cat.No. : CYB5A-11744H
Product Overview : Recombinant Human CYB5A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-108a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CYB5A cytochrome b5 type A (microsomal) [ Homo sapiens ]
Official Symbol : CYB5A
Synonyms : CYB5A; cytochrome b5 type A (microsomal); CYB5, cytochrome b 5 , cytochrome b5 (microsomal); cytochrome b5; type 1 cyt-b5; CYB5; MCB5;
Gene ID : 1528
mRNA Refseq : NM_001190807
Protein Refseq : NP_001177736
MIM : 613218
UniProt ID : P00167
Chromosome Location : 18q23
Pathway : Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Vitamin C (ascorbate) metabolism, organism-specific biosystem; gamma-linolenate biosynthesis II (animals), organism-specific biosystem; gamma-linolenate biosynthesis II (animals), conserved biosystem;
Function : aldo-keto reductase (NADP) activity; cytochrome-c oxidase activity; enzyme binding; heme binding; metal ion binding;

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