Recombinant Human DRD5, His-tagged DRD5-12165H

Recombinant Human DRD5, His-tagged

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Recombinant Human DRD5, His-tagged

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Cat.No. : DRD5-12165H
Product Overview : Recombinant Human DRD5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
Source : E.coli
Species : Human
Tag : His
Protein length : C-term-127a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : DRD5 dopamine receptor D5 [ Homo sapiens ]
Official Symbol : DRD5
Synonyms : DRD5; dopamine receptor D5; DRD1L2; D(1B) dopamine receptor; DRD1B; dopamine D5 receptor; dopamine receptor D1B; d(5) dopamine receptor; D1beta dopamine receptor; DBDR; MGC10601;
Gene ID : 1816
mRNA Refseq : NM_000798
Protein Refseq : NP_000789
UniProt ID : P21918
Chromosome Location : 4p16.1
Pathway : Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dopamine receptors, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem;
Function : G-protein alpha-subunit binding; G-protein coupled receptor activity; dopamine binding; dopamine receptor activity; dopamine receptor activity, coupled via Gs; drug binding; receptor activity; signal transducer activity;

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