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Recombinant Human DYRK1B, GST-tagged

Cat.No.: DYRK1B-12237H
Product Overview: Recombinant Human DYRK1B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.
Source: E.coli
Species: Human
Tag: GST
Protein length: 111-431a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B [ Homo sapiens ]
Official Symbol: DYRK1B
Synonyms: DYRK1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; minibrain related kinase; MIRK; mirk protein kinase; minibrain-related kinase;
Gene ID: 9149
mRNA Refseq: NM_004714
Protein Refseq: NP_004705
MIM: 604556
UniProt ID: Q9Y463
Chromosome Location: 19q12-q13.1
Function: ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; transcription coactivator activity;

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