Recombinant Human EPAS1, GST-tagged
Cat.No. : | EPAS1-12475H |
Product Overview : | Recombinant Human EPAS1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-350a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | EPAS1 endothelial PAS domain protein 1 [ Homo sapiens ] |
Official Symbol : | EPAS1 |
Synonyms : | EPAS1; endothelial PAS domain protein 1; endothelial PAS domain-containing protein 1; bHLHe73; HIF 1 alpha like factor; HIF2A; HLF; MOP2; PASD2; EPAS-1; HIF2-alpha; HIF-2-alpha; HIF-1alpha-like factor; HIF-1-alpha-like factor; member of PAS protein 2; PAS domain-containing protein 2; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; basic-helix-loop-helix-PAS protein MOP2; class E basic helix-loop-helix protein 73; ECYT4; |
Gene ID : | 2034 |
mRNA Refseq : | NM_001430 |
Protein Refseq : | NP_001421 |
MIM : | 603349 |
UniProt ID : | Q99814 |
Chromosome Location : | 2p21-p16 |
Pathway : | Adipogenesis, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Renal cell carcinoma, organism-specific biosystem; Renal cell carcinoma, conserved biosystem; Signaling events mediated by VEGFR1 and VEGFR2, organism-specific biosystem; |
Function : | DNA binding; histone acetyltransferase binding; protein binding; protein heterodimerization activity; contributes_to sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription fact |
Products Types
◆ Recombinant Protein | ||
EPAS1-2808M | Recombinant Mouse EPAS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPAS1-3349H | Recombinant Human EPAS1 Protein, GST-tagged | +Inquiry |
EPAS1-1772R | Recombinant Rat EPAS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPAS1-2173H | Recombinant Human EPAS1 Protein, His-tagged | +Inquiry |
EPAS1-29318TH | Recombinant Human EPAS1 | +Inquiry |
◆ Lysates | ||
EPAS1-6588HCL | Recombinant Human EPAS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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