Recombinant Human ERC1, His-tagged

• Cat.No.: ERC1-12519H
• Product Overview: Recombinant Human ERC1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-132a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ERC1 ELKS/RAB6-interacting/CAST family member 1 [ Homo sapiens ]
• Official Symbol: ERC1
• Synonyms: ERC1; ELKS/RAB6-interacting/CAST family member 1; RAB6 interacting protein 2 , RAB6IP2; ELKS/Rab6-interacting/CAST family member 1; CAST2; ELKS; KIAA1081; MGC12974; RAB6 interacting protein 2; Rab6-interacting protein 2; Cast2; RAB6IP2; FLJ31750
• Gene ID: 23085
• mRNA Refseq: NM_178039
• Protein Refseq: NP_829883
• MIM: 607127
• UniProt ID: Q8IUD2
• Chromosome Location: 12p13.3
• Pathway: Canonical NF-kappaB pathway, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem
• Function: PDZ domain binding; Rab GTPase binding; leucine zipper domain binding; protein binding