Recombinant Human ETF1, GST-tagged
Cat.No. : | ETF1-12564H |
Product Overview : | Recombinant Human ETF1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-404a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ETF1 eukaryotic translation termination factor 1 [ Homo sapiens ] |
Official Symbol : | ETF1 |
Synonyms : | ETF1; eukaryotic translation termination factor 1; ERF, ERF1, SUP45L1; eukaryotic peptide chain release factor subunit 1; eRF1; polypeptide chain release factor 1; RF1; sup45 (yeast omnipotent suppressor 45) homolog like 1; TB3 1; protein Cl1; eukaryotic release factor 1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; ERF; ERF1; TB3-1; D5S1995; SUP45L1; MGC111066; |
Gene ID : | 2107 |
mRNA Refseq : | NM_004730 |
Protein Refseq : | NP_004721 |
MIM : | 600285 |
UniProt ID : | P62495 |
Chromosome Location : | 5q31.2 |
Pathway : | Eukaryotic Translation Termination, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; Translation, organism-specific biosystem; |
Function : | RNA binding; protein binding; ribosome binding; translation release factor activity; translation release factor activity, codon specific; translation termination factor activity; |
Products Types
◆ Recombinant Protein | ||
ETF1-1333R | Recombinant Rhesus Macaque ETF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Etf1-2878M | Recombinant Mouse Etf1 Protein, Myc/DDK-tagged | +Inquiry |
ETF1-1815R | Recombinant Rat ETF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ETF1-3514H | Recombinant Human ETF1 Protein, GST-tagged | +Inquiry |
ETF1-1397H | Recombinant Human ETF1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
ETF1-6533HCL | Recombinant Human ETF1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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