"FANCC" Related Products

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Recombinant Human FANCC, GST-tagged

Cat.No.: FANCC-12737H
Product Overview: Recombinant Human FANCC protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.
Source: E.coli
Species: Human
Tag: GST
Protein length: 206-558a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: FANCC Fanconi anemia, complementation group C [ Homo sapiens ]
Official Symbol: FANCC
Synonyms: FANCC; Fanconi anemia, complementation group C; FACC; Fanconi anemia group C protein; FA3; FAC; FLJ14675;
Gene ID: 2176
mRNA Refseq: NM_000136
Protein Refseq: NP_000127
MIM: 613899
UniProt ID: Q00597
Chromosome Location: 9q22.3
Pathway: BARD1 signaling events, organism-specific biosystem; DNA Repair, organism-specific biosystem; FA core complex, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem;
Function: protein binding;

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