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Recombinant Human FBLN1, GST-tagged

Cat.No.: FBLN1-12764H
Product Overview: Recombinant Human FBLN1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-300a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: FBLN1 fibulin 1 [ Homo sapiens ]
Official Symbol: FBLN1
Synonyms: FBLN1; fibulin 1; fibulin-1; FBLN; FIBL1;
Gene ID: 2192
mRNA Refseq: NM_001996
Protein Refseq: NP_001987
MIM: 135820
UniProt ID: P23142
Chromosome Location: 22q13.31
Function: calcium ion binding; extracellular matrix structural constituent; peptidase activator activity;

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