"FBXO32" Related Products

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Recombinant Human FBXO32, GST-tagged

Cat.No.: FBXO32-12796H
Product Overview: Recombinant Human FBXO32 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source: E.coli
Species: Human
Tag: GST
Protein length: C-term-217a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: FBXO32 F-box protein 32 [ Homo sapiens ]
Official Symbol: FBXO32
Synonyms: FBXO32; F-box protein 32; F box only protein 32; F-box only protein 32; ATROGIN1; Fbx32; MAFbx; atrogin 1; atrogin-1; muscle atrophy F-box protein; FLJ32424; MGC33610;
Gene ID: 114907
mRNA Refseq: NM_001242463
Protein Refseq: NP_001229392
MIM: 606604
UniProt ID: Q969P5
Chromosome Location: 8q24.13
Pathway: FoxO family signaling, organism-specific biosystem; Monoamine Transport, organism-specific biosystem;

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