Recombinant Human FBXW2, GST-tagged
Cat.No. : | FBXW2-12810H |
Product Overview : | Recombinant Human FBXW2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | N-term-314a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FBXW2 F-box and WD repeat domain containing 2 [ Homo sapiens ] |
Official Symbol : | FBXW2 |
Synonyms : | FBXW2; F-box and WD repeat domain containing 2; F box and WD 40 domain protein 2; F-box/WD repeat-containing protein 2; FBW2; Fwd2; Md6; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; MGC117371; |
Gene ID : | 26190 |
mRNA Refseq : | NM_012164 |
Protein Refseq : | NP_036296 |
MIM : | 609071 |
UniProt ID : | Q9UKT8 |
Chromosome Location : | 9q34 |
Pathway : | Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Protein folding, organism-specific biosystem; Wnt Signaling Pathway, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem; |
Function : | ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
FBXW2-3970H | Recombinant Human FBXW2 Protein, GST-tagged | +Inquiry |
FBXW2-1959R | Recombinant Rat FBXW2 Protein, His (Fc)-Avi-tagged | +Inquiry |
FBXW2-2302R | Recombinant Rat FBXW2 Protein | +Inquiry |
FBXW2-2668Z | Recombinant Zebrafish FBXW2 | +Inquiry |
FBXW2-1767C | Recombinant Chicken FBXW2 | +Inquiry |
◆ Lysates | ||
FBXW2-6285HCL | Recombinant Human FBXW2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket