Recombinant Human FER, His-tagged

• Cat.No.: FER-12842H
• Product Overview: Recombinant Human FER protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 96-445a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FER fer (fps/fes related) tyrosine kinase [ Homo sapiens ]
• Official Symbol: FER
• Synonyms: FER; fer (fps/fes related) tyrosine kinase; tyrosine-protein kinase Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1; regulatory subunit 74; TYK3; p94-Fer; tyrosine kinase 3; proto-oncogene c-Fer; feline encephalitis virus-related kinase FER; protein phosphatase 1, regulatory subunit 74; fujinami poultry sarcoma/Feline sarcoma-related protein Fer; FerT
• Gene ID: 2241
• mRNA Refseq: NM_005246
• Protein Refseq: NP_005237
• MIM: 176942
• UniProt ID: P16591
• Chromosome Location: 5q21
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; N-cadherin signaling events, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by SCF-KIT, organism-specific biosystem
• Function: ATP binding; Rab GTPase binding; actin binding; cadherin binding; epidermal growth factor receptor binding; gamma-catenin binding; lipid binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein kinase binding; protein t