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Recombinant Human FTCD, His-tagged

Cat.No.: FTCD-13023H
Product Overview: Recombinant Human FTCD protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: C-term-350a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: FTCD formiminotransferase cyclodeaminase [ Homo sapiens ]
Official Symbol: FTCD
Synonyms: FTCD; formiminotransferase cyclodeaminase; formimidoyltransferase-cyclodeaminase; formiminotransferase-cyclodeaminase; formimidoyltransferase cyclodeaminase; LCHC1;
Gene ID: 10841
mRNA Refseq: NM_006657
Protein Refseq: NP_006648
MIM: 606806
UniProt ID: O95954
Chromosome Location: 21q22.3
Pathway: Histidine catabolism, organism-specific biosystem; Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; One Carbon Metabolism, organism-specific biosystem;
Function: folic acid binding; formimidoyltetrahydrofolate cyclodeaminase activity; glutamate formimidoyltransferase activity; lyase activity; transferase activity;

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