Recombinant Human FTCD Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FTCD-5746H
• Product Overview: FTCD MS Standard C13 and N15-labeled recombinant protein (NP_006648) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 58.9 kDa
• AA Sequence: MSQLVECVPNFSEGKNQEVIDAISG AITQTPGCVLLDVDAGPSTNRTVYT FVGPPECVVEGALNAARVASRLIDM SRHQGEHPRMGALDVCPFIPVRGVS VDECVLCAQAFGQRLAEELDVPVYL YGEAARMDSRRTLPAIRAGEYEALP KKLQQADWAPDFGPSSFVPSWGATA TGARKFLIAFNINLLGTKEQAHRIA LNLREQGRGKDQPGRLKKVQGIGWY LDEKNLAQVSTNLLDFEVTALHTVY EETCREAQELSLPVVGSQLVGLVPL KALLDAAAFYCEKENLFILEEEQRI RLVVSRLGLDSLCPFSPKERIIEYL VPERGPERGLGSKSLRAFVGEVGAR SAAPGGGSVAAAAAAMGAALGSMVG LMTYGRRQFQSLDTTMRRLIPPFRE ASAKLTTLVDADAEAFTAYLEAMRL PKNTPEEKDRRTAALQEGLRRAVSV PLTLAETVASLWPALQELARCGNLA CRSDLQVAAKALEMGVFGAYFNVLI NLRDITDEAFKDQIHHRVSSLLQEA KTQAALVLDCLETRQETRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FTCD formiminotransferase cyclodeaminase [ Homo sapiens (human) ]
• Official Symbol: FTCD
• Synonyms: FTCD; formiminotransferase cyclodeaminase; formimidoyltransferase-cyclodeaminase; formiminotransferase-cyclodeaminase; formimidoyltransferase cyclodeaminase; LCHC1
• Gene ID: 10841
• mRNA Refseq: NM_006657
• Protein Refseq: NP_006648
• MIM: 606806
• UniProt ID: O95954