Recombinant Human FUS, GST-tagged
Cat.No. : | FUS-13037H |
Product Overview : | Recombinant Human FUS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 52-400a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FUS fused in sarcoma [ Homo sapiens ] |
Official Symbol : | FUS |
Synonyms : | FUS; fused in sarcoma; ALS6, amyotrophic lateral sclerosis 6 , fusion (involved in t(12;16) in malignant liposarcoma) , fusion, derived from t(12;16) malignant liposarcoma; RNA-binding protein FUS; FUS1; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; TLS; translocated in liposarcoma; oncogene FUS; oncogene TLS; fus-like protein; 75 kDa DNA-pairing protein; fusion gene in myxoid liposarcoma; translocated in liposarcoma protein; ALS6; POMP75; HNRNPP2; |
Gene ID : | 2521 |
mRNA Refseq : | NM_001170634 |
Protein Refseq : | NP_001164105 |
MIM : | 137070 |
UniProt ID : | P35637 |
Chromosome Location : | 16p11.2 |
Pathway : | Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem; |
Function : | DNA binding; RNA binding; metal ion binding; nucleotide binding; protein binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
FUS-06H | Active Recombinant Human FUS Protein, Myc/DDK-tagged | +Inquiry |
FUS-4555H | Recombinant Human FUS Protein, GST-tagged | +Inquiry |
FUS-947H | Recombinant Human FUS Protein, His (Fc)-Avi-tagged | +Inquiry |
FUS-461H | Recombinant Human FUS Protein, His-tagged | +Inquiry |
Fus-3107M | Recombinant Mouse Fus Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
FUS-6118HCL | Recombinant Human FUS 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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