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Recombinant Human GADD45A, GST-tagged

Cat.No.: GADD45A-13109H
Product Overview: Recombinant Human GADD45A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: 5-165a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: GADD45A growth arrest and DNA-damage-inducible, alpha [ Homo sapiens ]
Official Symbol: GADD45A
Synonyms: GADD45A; growth arrest and DNA-damage-inducible, alpha; DDIT1; growth arrest and DNA damage-inducible protein GADD45 alpha; GADD45; DDIT-1; DNA damage-inducible transcript-1; DNA-damage-inducible transcript 1; DNA damage-inducible transcript 1 protein; growth arrest and DNA-damage-inducible 45 alpha;
Gene ID: 1647
mRNA Refseq: NM_001199741
Protein Refseq: NP_001186670
MIM: 126335
UniProt ID: P24522
Chromosome Location: 1p31.2
Pathway: ATF-2 transcription factor network, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Direct p53 effectors, organism-specific biosystem;
Function: protein binding;

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