Recombinant Human GADD45A, GST-tagged
Cat.No. : | GADD45A-13109H |
Product Overview : | Recombinant Human GADD45A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 5-165a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | GADD45A growth arrest and DNA-damage-inducible, alpha [ Homo sapiens ] |
Official Symbol : | GADD45A |
Synonyms : | GADD45A; growth arrest and DNA-damage-inducible, alpha; DDIT1; growth arrest and DNA damage-inducible protein GADD45 alpha; GADD45; DDIT-1; DNA damage-inducible transcript-1; DNA-damage-inducible transcript 1; DNA damage-inducible transcript 1 protein; growth arrest and DNA-damage-inducible 45 alpha; |
Gene ID : | 1647 |
mRNA Refseq : | NM_001199741 |
Protein Refseq : | NP_001186670 |
MIM : | 126335 |
UniProt ID : | P24522 |
Chromosome Location : | 1p31.2 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Direct p53 effectors, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
GADD45A-4657H | Recombinant Human GADD45A Protein, GST-tagged | +Inquiry |
Gadd45a-3130M | Recombinant Mouse Gadd45a Protein, Myc/DDK-tagged | +Inquiry |
GADD45A-941H | Recombinant Human GADD45A Protein, MYC/DDK-tagged | +Inquiry |
GADD45A-1619R | Recombinant Rhesus Macaque GADD45A Protein, His (Fc)-Avi-tagged | +Inquiry |
GADD45A-3439M | Recombinant Mouse GADD45A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GADD45A-575HCL | Recombinant Human GADD45A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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