Recombinant Human GLUD2, GST-tagged
Cat.No. : | GLUD2-13320H |
Product Overview : | Recombinant Human GLUD2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 207-558a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | GLUD2 glutamate dehydrogenase 2 [ Homo sapiens ] |
Official Symbol : | GLUD2 |
Synonyms : | GLUD2; glutamate dehydrogenase 2; GLUDP1, glutamate dehydrogenase pseudogene 1; glutamate dehydrogenase 2, mitochondrial; GDH 2; glutamate dehydrogenase pseudogene 1; GDH2; GLUDP1; |
Gene ID : | 2747 |
mRNA Refseq : | NM_012084 |
Protein Refseq : | NP_036216 |
MIM : | 300144 |
UniProt ID : | P49448 |
Chromosome Location : | Xq24-q25 |
Pathway : | Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; D-Glutamine and D-glutamate metabolism, organism-specific biosystem; D-Glutamine and D-glutamate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | ADP binding; GTP binding; glutamate dehydrogenase (NAD+) activity; glutamate dehydrogenase [NAD(P)+] activity; leucine binding; nucleotide binding; oxidoreductase activity; |
Products Types
◆ Recombinant Protein | ||
GLUD2-90H | Recombinant Human GLUD2, GST-tagged | +Inquiry |
GLUD2-27654TH | Recombinant Human GLUD2, His-tagged | +Inquiry |
GLUD2-89H | Recombinant Human GLUD2, GST-tagged | +Inquiry |
◆ Lysates | ||
GLUD2-716HCL | Recombinant Human GLUD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionAltered GLUD2 activity can impact brain metabolism and contribute to metabolic and neurological disorders.
Genetic mutations in GLUD2 can affect its function, potentially leading to neurological imbalances.
It helps regulate neurotransmitter levels by converting glutamate to α-ketoglutarate.
Targeting GLUD2 could provide new treatments for conditions related to neurotransmitter imbalances.
GLUD2 is important for brain function, influencing neurotransmitter balance and neuronal activity.
GLUD2 interacts with energy metabolism pathways in the brain, affecting neuronal energy supply.
GLUD2, a glutamate dehydrogenase, is key in metabolizing glutamate, an important amino acid in the brain.
Customer Reviews (3)
Write a reviewConsistency in quality. Supports our research consistently.
Precision in analysis. Vital for our research goals.
Expert service quality. Aids our research significantly.
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