Recombinant Human GNPDA1, GST-tagged GNPDA1-13375H

Recombinant Human GNPDA1, GST-tagged


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Recombinant Human GNPDA1, GST-tagged

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Cat.No. : GNPDA1-13375H
Product Overview : Recombinant Human GNPDA1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : GDP-mannose 4,6-dehydratase (GMD; EC catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-289a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : GNPDA1 glucosamine-6-phosphate deaminase 1 [ Homo sapiens ]
Official Symbol : GNPDA1
Synonyms : GNPDA1; glucosamine-6-phosphate deaminase 1; glucosamine 6 phosphate isomerase , GNPI; glucosamine-6-phosphate isomerase 1; glucosamine 6 phosphate deaminase; GNPDA; GPI; HLN; KIAA0060; oscillin; GNPDA 1; glcN6P deaminase 1; GNP1; GNPI;
Gene ID : 10007
mRNA Refseq : NM_005471
Protein Refseq : NP_005462
MIM : 601798
UniProt ID : P46926
Chromosome Location : 5q21
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; N-acetylglucosamine degradation I, organism-specific biosystem; N-acetylglucosamine degradation II, organism-specific biosystem; UDP-N-acetyl-D-galactosamine biosynthesis II, organism-specific biosystem;
Function : glucosamine-6-phosphate deaminase activity; hydrolase activity;

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