"GPM6A" Related Products

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Recombinant Human GPM6A, GST-tagged

Cat.No.: GPM6A-13428H
Product Overview: Recombinant Human GPM6A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-278a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: GPM6A glycoprotein M6A [ Homo sapiens ]
Official Symbol: GPM6A
Synonyms: GPM6A; glycoprotein M6A; GPM6; neuronal membrane glycoprotein M6-a; M6A;
Gene ID: 2823
mRNA Refseq: NM_005277
Protein Refseq: NP_005268
MIM: 601275
UniProt ID: P51674
Chromosome Location: 4q34
Function: calcium channel activity;

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