Recombinant Human GPR77, GST-tagged

• Cat.No.: GPR77-13488H
• Product Overview: Recombinant Human GPR77 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-115a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GPR77 G protein-coupled receptor 77 [ Homo sapiens ]
• Official Symbol: GPR77
• Synonyms: GPR77; G protein-coupled receptor 77; C5a anaphylatoxin chemotactic receptor C5L2; C5L2; G-protein coupled receptor 77; G protein-coupled receptor C5L2; GPF77
• Gene ID: 27202
• mRNA Refseq: NM_018485
• Protein Refseq: NP_060955
• MIM: 609949
• UniProt ID: Q9P296
• Chromosome Location: 19q13.33
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem
• Function: C5a anaphylatoxin receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity