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Recombinant Human GTF2H3, His-tagged

Cat.No. : GTF2H3-13598H
Product Overview : Recombinant Human GTF2H3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
Source : E.coli
Species : Human
Tag : His
Protein length : 24-210a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa [ Homo sapiens ]
Official Symbol : GTF2H3
Synonyms : GTF2H3; general transcription factor IIH, polypeptide 3, 34kDa; general transcription factor IIH, polypeptide 3 (34kD subunit); general transcription factor IIH subunit 3; BTF2; TFIIH; BTF2 p34; basic transcription factor 2 34 kDa subunit; general transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunit; TFB4;
Gene ID : 2967
mRNA Refseq : NM_001516
Protein Refseq : NP_001507
MIM : 601750
UniProt ID : Q13889
Chromosome Location : 12q24.31
Pathway : Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem;
Function : contributes_to DNA-dependent ATPase activity; contributes_to RNA polymerase II carboxy-terminal domain kinase activity; damaged DNA binding; metal ion binding; protein N-terminus binding; contributes_to protein kinase activity; sequence-specific DNA bindi

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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