"GTF2H3" Related Products


Recombinant Human GTF2H3, His-tagged

Cat.No.: GTF2H3-13598H
Product Overview: Recombinant Human GTF2H3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
Source: E.coli
Species: Human
Tag: His
Protein length: 24-210a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa [ Homo sapiens ]
Official Symbol: GTF2H3
Synonyms: GTF2H3; general transcription factor IIH, polypeptide 3, 34kDa; general transcription factor IIH, polypeptide 3 (34kD subunit); general transcription factor IIH subunit 3; BTF2; TFIIH; BTF2 p34; basic transcription factor 2 34 kDa subunit; general transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunit; TFB4;
Gene ID: 2967
mRNA Refseq: NM_001516
Protein Refseq: NP_001507
MIM: 601750
UniProt ID: Q13889
Chromosome Location: 12q24.31
Pathway: Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem;
Function: contributes_to DNA-dependent ATPase activity; contributes_to RNA polymerase II carboxy-terminal domain kinase activity; damaged DNA binding; metal ion binding; protein N-terminus binding; contributes_to protein kinase activity; sequence-specific DNA bindi

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