Recombinant Human HARS2, GST-tagged

• Cat.No.: HARS2-13670H
• Product Overview: Recombinant Human HARS2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-350a.a.(C-164a.a.)
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HARS2 histidyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens ]
• Official Symbol: HARS2
• Synonyms: HARS2; histidyl-tRNA synthetase 2, mitochondrial (putative); HARSL, histidyl tRNA synthetase like; probable histidine--tRNA ligase, mitochondrial; HARSR; histidine tRNA ligase 2; mitochondrial (putative); HO3; hisRS; HARS-related; histidine translase; histidine-tRNA ligase homolog; probable histidyl-tRNA synthetase, mitochondrial; histidine tRNA ligase 2, mitochondrial (putative); HARSL
• Gene ID: 23438
• mRNA Refseq: NM_012208
• Protein Refseq: NP_036340
• MIM: 600783
• UniProt ID: P49590
• Chromosome Location: 5q31.3
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem
• Function: ATP binding; histidine-tRNA ligase activity; ligase activity; nucleotide binding