"HSD17B3" Related Products

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Recombinant Human HSD17B3, GST-tagged

Cat.No.: HSD17B3-13959H
Product Overview: Recombinant Human HSD17B3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Source: E.coli
Species: Human
Tag: GST
Protein length: 25-177a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 [ Homo sapiens ]
Official Symbol: HSD17B3
Synonyms: HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3; testosterone 17-beta-dehydrogenase 3; SDR12C2; short chain dehydrogenase/reductase family 12C; member 2; 17-beta-HSD3; 17-beta-HSD 3; 17-beta-hydroxysteroid dehydrogenase type 3; testicular 17-beta-hydroxysteroid dehydrogenase; short chain dehydrogenase/reductase family 12C, member 2; EDH17B3;
Gene ID: 3293
mRNA Refseq: NM_000197
Protein Refseq: NP_000188
MIM: 605573
UniProt ID: P37058
Chromosome Location: 9q22
Pathway: Androgen biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Steroid Biosynthesis, organism-specific biosystem; Steroid hormone biosynthesis, organism-specific biosystem;
Function: estradiol 17-beta-dehydrogenase activity; nucleotide binding; oxidoreductase activity; testosterone 17-beta-dehydrogenase (NAD+) activity; testosterone 17-beta-dehydrogenase (NADP+) activity;

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