"IL18BP" Related Products

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Recombinant Human IL18BP, GST-tagged

Cat.No.: IL18BP-14162H
Product Overview: Recombinant Human IL18BP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohns disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: 30-194a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: IL18BP interleukin 18 binding protein [ Homo sapiens ]
Official Symbol: IL18BP
Synonyms: IL18BP; interleukin 18 binding protein; interleukin-18-binding protein; IL18BPa; MC51L 53L 54L homolog gene product; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product;
Gene ID: 10068
mRNA Refseq: NM_001039659
Protein Refseq: NP_001034748
MIM: 604113
UniProt ID: O95998
Chromosome Location: 11q13
Function: interleukin-18 binding; receptor antagonist activity;

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