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Recombinant human TAF15, His-tagged

Cat.No. : TAF15-2466H
Product Overview : Recombinant human TAF15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : TAF15 is a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT.
Molecular Mass : 30kDa (282aa), confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSSYHSQRE NYSHHTQDDR RDVSRYGEDN RGYGGSQGGG RGRGGYDKDG RGPMTGSSGG DRGGFKNFGGHRDYGPRTDA DSESDNSDNN TIFVQGLGEG VSTDQVGEFF KQIGIIKTNK KTGKPMINLY TDKDTGKPKG EATVSFDDPP SAKAAIDWFD GKEFHGNIIK VSFATRRPEF MRGGGSGGGR RGRGGYRGRG GFQGRGGDPK SGDWVCPNPS CGNMNFARRN SCNQCNEPRP EDSRPSGGDFRGRGYGGERG YR
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa [ Homo sapiens ]
Official Symbol : TAF15
Synonyms : TAF15; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TAF2N, TATA box binding protein (TBP) associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56); TATA-binding protein-associated factor 2N; hTAFII68; Npl3; RBP56; TAF(II)68; RBP56/CSMF fusion; TBP-associated factor 15; 68 kDa TATA-binding protein-associated factor; TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TAF2N; TAFII68;
Gene ID : 8148
mRNA Refseq : NM_003487
Protein Refseq : NP_003478
MIM : 601574
UniProt ID : Q92804
Chromosome Location : 17q11.1-q11.2
Pathway : Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Function : DNA binding; RNA binding; metal ion binding; nucleotide binding; protein binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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