Recombinant Human XRN1, His-tagged
Cat.No. : | XRN1-102H |
Product Overview : | The protein was expressed as 6*his-tagged fusion protein by E.Coli and puri?ed by Ni-sepharose. |
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Description : | SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. |
Source : | E.Coli |
Species : | Human |
Tag : | His |
AA Sequence : | 222-576aa |
Storage : | The protein is stored in PBS bu?er at -20 oC. Repeated freezethaw cycles should be avoided. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | XRN1 5'-3' exoribonuclease 1 [ Homo sapiens (human) ] |
Official Symbol : | XRN1 |
Synonyms : | XRN1; SEP1; 5'-3' exoribonuclease 1; strand-exchange protein 1 homolog |
Gene ID : | 54464 |
mRNA Refseq : | NM_019001 |
Protein Refseq : | NP_061874 |
MIM : | 607994 |
UniProt ID : | Q8IZH2 |
Chromosome Location : | 3q23 |
Pathway : | Deadenylation-dependent mRNA decay; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1); Destabilization of mRNA by Tristetraprolin (TTP) |
Function : | 5'-3' exonuclease activity; DNA binding; RNA binding; protein binding |
Products Types
◆ Recombinant Protein | ||
XRN1-101H | Recombinant Human XRN1, GST-tagged | +Inquiry |
XRN1-11265Z | Recombinant Zebrafish XRN1 | +Inquiry |
Xrn1-7912R | Recombinant Rat Xrn1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
XRN1-1940HCL | Recombinant Human XRN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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