Recombinant Human PSME3 protein, His-tagged
Cat.No. : | PSME3-359H |
Product Overview : | Recombinant Human PSME3 (Met1-Tyr254) protein was fused to His-tag at N-terminus and expressed in E.coli. |
- Specification
- Gene Information
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Description : | Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Met1 |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 30.3 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | Met1-Tyr254 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PSME3 |
Official Symbol : | PSME3 |
Synonyms : | PSME3; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki); proteasome activator complex subunit 3; Ki; PA28 gamma; PA28G; REG GAMMA; PA28gamma; Ki antigen; Ki nuclear autoantigen; proteasome activator 28-gamma; 11S regulator complex gamma subunit; 11S regulator complex subunit gamma; proteasome activator 28 subunit gamma; activator of multicatalytic protease subunit 3; REG-GAMMA; PA28-gamma |
Gene ID : | 10197 |
mRNA Refseq : | NM_005789 |
Protein Refseq : | NP_005780 |
MIM : | 605129 |
UniProt ID : | P61289 |
Products Types
◆ Recombinant Protein | ||
PSME3-1785H | Recombinant Human PSME3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSME3-7228M | Recombinant Mouse PSME3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSME3-570C | Recombinant Cynomolgus Monkey PSME3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Psme3-5203M | Recombinant Mouse Psme3 Protein, Myc/DDK-tagged | +Inquiry |
PSME3-827C | Recombinant Cynomolgus PSME3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PSME3-2740HCL | Recombinant Human PSME3 293 Cell Lysate | +Inquiry |
PSME3-2739HCL | Recombinant Human PSME3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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