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Recombinant Human PACSIN2, His-tagged

Cat.No. : PACSIN2-167H
Product Overview : Recombinant Human Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2/PACSIN2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Gln486) of Human PACSIN2 fused with a polyhistidine tag at the C-terminus.
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Description : Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization.
Source : HEK293
Species : Human
Tag : His
AA Sequence : MSVTYDDSVGVEVSSDSFWEVGNYK RTVKRIDDGHRLCSDLMNCLHERAR IEKAYAQQLTEWARR WRQLVEKGPQYGTVEKAWMAFMSEA ERVSELHLEVKASLMNDDFEKIKNW QKEAFHKQMMGGFKE TKEAEDGFRKAQKPWAKKLKEVEAA KKAHHAACKEEKLAISREANSKADP SLNPEQLKKLQDKIE KCKQDVLKTKEKYEKSLKELDQGTP QYMENMEQVFEQCQQFEEKRLRFFR EVLLEVQKHLDLSNV AGYKAIYHDLEQSIRAADAVEDLRW FRANHGPGMAMNWPQFEEWSADLNR TLSRREKKKATDGVT LTGINQTGDQSLPSKPSSTLNVPSN PAQSAQSQSSYNPFEDEDDTGSTVS EKDDTKAKNVSSYEK TQSYPTDWSDDESNNPFSSTDANGD SNPFDDDATSGTEVRVRALYDYEGQ EHDELSFKAGDELTK MEDEDEQGWCKGRLDNGQVGLYPAN YVEAIQVDHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Gene Name : PACSIN2 protein kinase C and casein kinase substrate in neurons 2 [ Homo sapiens ]
Official Symbol : PACSIN2
Synonyms : PACSIN2; protein kinase C and casein kinase substrate in neurons 2; protein kinase C and casein kinase substrate in neurons protein 2; SDPII; syndapin II; cytoplasmic phosphoprotein PACSIN2;
Gene ID : 11252
mRNA Refseq : NM_001184970
Protein Refseq : NP_001171899
MIM : 604960
UniProt ID : Q9UNF0
Chromosome Location : 22q13.2-q13.33
Function : cytoskeletal protein binding; transporter activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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