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Native Human Kallikrein

Cat.No.: KLKB1-210H
Product Overview: Purified Native Human Urine Kallikrein. CAS Number: 9001-01-8; E.C. Number: 3.4.21.35
Description: Human Kallikrein protein, also known as Urokallikrein, is an enzyme present in blood plasma, lymph, urine, saliva, pancreatic juices, and other body fluids that catalyzes the proteolysis of bradykininogen to bradykinin. Also called kininogenase.Kallikrein is the target of an active investigation by drug researchers as possible bio-marker for cancer.
Source: Human Urine
Species: Human
Form: Liquid in proprietary buffer
Bio-activity: >10 pNA units/mL
Molecular Mass: 44000
Purity: >99% (SDS-PAGE)
Unit Definition: One unit will hydrolize 1.0 umole of H-D-Val-Leu-Arg-pNA(S-2266) per minute at pH 8.0 at 37C
Storage: Store at 2-8 °C.
Gene Name: KLKB1 kallikrein B, plasma (Fletcher factor) 1 [ Homo sapiens ]
Official Symbol: KLKB1
Synonyms: KLKB1; kallikrein B, plasma (Fletcher factor) 1; KLK3; plasma kallikrein; kininogenin; Fletcher factor; plasma prekallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; PPK;
Gene ID: 3818
mRNA Refseq: NM_000892
Protein Refseq: NP_000883
MIM: 229000
UniProt ID: P03952
Chromosome Location: 4q35
Pathway: Activation of Matrix Metalloproteinases, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem;
Function: peptidase activity; protein binding; serine-type endopeptidase activity;

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