"UBA1" Related Products


Recombinant Human UBA1, GST-tagged

Cat.No.: UBA1-832H
Product Overview: Recombinant full-length human UBA1 (UBE1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: UBA1 or ubiquitin-like modifier activating enzyme 1 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins and catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. UBE1 is able to transfer ubiquitin to a wide range of E2 substrates. UBA1 protein may participate in DNA topoisomerase-2 activity. UBA1 complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair.
Source: Sf9 insect cells using baculovirus
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass: ~145 kDa
Protein length: Full length
Purity: >95%
Applications: Western Blot
Stability: 1yr at –70°C from date of shipment
Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1ug/ul
Gene Name: UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ]
Official Symbol: UBA1
Synonyms: UBA1; ubiquitin-like modifier activating enzyme 1; A1S9T, GXP1, UBE1, ubiquitin activating enzyme E1 , ubiquitin activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing); ubiquitin-like modifier-activating enzyme 1; POC20; POC20 centriolar protein homolog (Chlamydomonas); ubiquitin activating enzyme E1 homolog (yeast); UBE1X; POC20 centriolar protein homolog; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; MGC4781;
Gene ID: 7317
mRNA Refseq: NM_003334
Protein Refseq: NP_003325
MIM: 314370
UniProt ID: P22314
Chromosome Location: Xp11.23
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Function: ATP binding; ligase activity; nucleotide binding; protein binding; small protein activating enzyme activity;

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