Recombinant Human UBA7, GST-tagged
Cat.No. : | UBA7-833H |
Product Overview : | Recombinant full-length human UBA7 (UBE1L) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | UBA7 or or ubiquitin-like modifier activating enzyme 7 is a member of the E1 ubiquitin-activating enzyme family which is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. UBA7 is expressed in a variety of tissues, including normal lung, but highly expressed in a large series of lung cancer cell lines. UBA7 may represent a second, autosomal member of the ubiquitin-activating gene family, which play a role in the ubiquitin conjugation pathway, which is of central importance in all eukaryotes. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~138 kDa |
Protein length : | Full length |
Purity : | >95% |
Applications : | Western Blot |
Stability : | 1yr at –70°C from date of shipment |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1ug/ul |
Gene Name : | UBA7 ubiquitin-like modifier activating enzyme 7 [ Homo sapiens ] |
Official Symbol : | UBA7 |
Synonyms : | UBA7; ubiquitin-like modifier activating enzyme 7; UBE1L, ubiquitin activating enzyme E1 like; ubiquitin-like modifier-activating enzyme 7; D8; UBA1; ubiquitin activating enzyme E1 homolog B (yeast); UBA1B; ubiquitin activating enzyme E1; UBE2; ubiquitin-activating enzyme 7; ubiquitin-activating enzyme-2; UBA7, ubiquitin-activating enzyme E1; ubiquitin-activating enzyme E1 homolog; UBA1, ubiquitin-activating enzyme E1 homolog B; ubiquitin-activating enzyme E1-related protein; UBE1L; MGC12713; |
Gene ID : | 7318 |
mRNA Refseq : | NM_003335 |
Protein Refseq : | NP_003326 |
MIM : | 191325 |
UniProt ID : | P41226 |
Chromosome Location : | 3p21 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; |
Function : | ATP binding; ISG15 activating enzyme activity; ligase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
Uba7-6770M | Recombinant Mouse Uba7 Protein, Myc/DDK-tagged | +Inquiry |
UBA7-0050H | Recombinant Human UBA7 Protein (D2-L1012), Tag Free | +Inquiry |
UBA7-2291H | Recombinant Human UBA7 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBA7-0051H | Recombinant Human UBA7 Protein (D2-L1012), His/Strep tagged | +Inquiry |
UBA7-171H | Active Recombinant Human UBA7, His-tagged | +Inquiry |
◆ Lysates | ||
UBA7-601HCL | Recombinant Human UBA7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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