Recombinant Mouse Angpt2, FLAG-tagged

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Recombinant Mouse Angpt2, FLAG-tagged

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Cat.No. : Angpt2-88M
Product Overview : Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG-tag.
Description : Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
Source : HEK293 Cells
Species : Mouse
Tag : FLAG
Form : Lyophilized. Contains PBS with trehalose and Brij35.
Molecular Mass : ~70kDa (SDS-PAGE)
Purity : ≥95% (SDS-PAGE)
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration : 0.1 mg /ml after reconstitution.
Gene Name : Angpt2 angiopoietin 2 [ Mus musculus ]
Official Symbol : Angpt2
Synonyms : ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; Agpt2; Ang-2;
Gene ID : 11601
mRNA Refseq : NM_007426
Protein Refseq : NP_031452
Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Tie2 Signaling, organism-specific biosystem;
Function : metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding; vascular endothelial growth factor receptor binding;

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