Recombinant Human FASLG, Fc-tagged FASLG-245H

Recombinant Human FASLG, Fc-tagged

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Recombinant Human FASLG, Fc-tagged

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Specification Gene Information Related Products
Cat.No. : FASLG-245H
Product Overview : Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1.
Description : Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Source : HEK293 Cells
Species : Human
Tag : Fc
Form : Lyophilized. Contains PBS.
Bio-activity : Induces apoptosis of human Jurkat T cells at a concentration of<0.2ng l.>
Molecular Mass : ~50kDa (SDS-PAGE)
Purity : ≥95% (SDS-PAGE)
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration : 0.1mg/ml after reconstitution.
Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ]
Official Symbol : FASLG
Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1;
Gene ID : 356
mRNA Refseq : NM_000639
Protein Refseq : NP_000630
MIM : 134638
UniProt ID : P48023
Chromosome Location : 1q23
Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem;
Function : cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;

Products Types

◆ Recombinant Protein

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◆ Lysates

FASLG-6324HCLRecombinant Human FASLG 293 Cell Lysate+Inquiry

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Related Gene

FASLG

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