Recombinant Mouse Il4, His-tagged
Cat.No. : | Il4-315M |
Product Overview : | Mouse IL-4 (aa 21-140) is fused at the N-terminus to a His-tag. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-γ, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from 0.2μm-filtered solution in PBS (pH 7.4). |
Purity : | ≥98% (SDS-PAGE) |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles. |
Gene Name : | Il4 interleukin 4 [ Mus musculus ] |
Official Symbol : | Il4 |
Synonyms : | IL4; interleukin 4; interleukin-4; IGG1 induction factor; B-cell growth factor 1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1; B-cell IgG differentiation factor; Il-4; BSF-1; |
Gene ID : | 16189 |
mRNA Refseq : | NM_021283 |
Protein Refseq : | NP_067258 |
Pathway : | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | cytokine activity; cytokine receptor binding; growth factor activity; interleukin-4 receptor binding; |
Products Types
◆ Recombinant Protein | ||
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IL4-094I | Active Recombinant Human IL4 Protein (130 aa) | +Inquiry |
IL4-4323O | Recombinant Ovine IL4 Protein | +Inquiry |
IL4-0017H | Recombinant Human IL4 Protein | +Inquiry |
IL4-2702R | Recombinant Rat IL4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL4-001MCL | Recombinant Mouse IL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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