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Recombinant Mouse Kitlg, Fc-tagged

Cat.No.: Kitlg-486M
Product Overview: The extracellular domain of mouse SCF (aa 26-214) is fused to the N-terminus of the Fc region of mouse IgG2a.
Description: Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
Source: CHO Cells
Species: Mouse
Tag: Fc
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Purity: ≥98% (SDS-PAGE)
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles.
Gene Name: Kitl?kit ligand [?Mus musculus?(house mouse) ]
Official Symbol: Kitlg
Synonyms: Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted; kit ligand; cloud gray; C-kit ligand; Steel factor; grizzle-belly; stem cell factor; mast cell growth factor; hematopoietic growth factor KL
Gene ID: 17311
mRNA Refseq: NM_013598
Protein Refseq: ?NP_038626
UniProt ID: P20826
Chromosome Location: 10 D1; 10 51.4 cM
Pathway: Adaptive Immune System; Constitutive PI3K/AKT Signaling in Cancer; Cytokine-cytokine receptor interaction
Function: cytokine activity; growth factor activity; protein binding

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