"IL1RL1" Related Products

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Recombinant Human IL1RL1, Fc-tagged

Cat.No.: IL1RL1-502H
Product Overview: Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
Description: The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
Source: HEK293 Cells
Species: Human
Tag: Fc
Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
Bio-activity: Interacts with human IL-33.
Molecular Mass: ~90kDa (SDS-PAGE)
Purity: ≥90% (SDS-PAGE)
Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Concentration: ~0.5mg/ml
Gene Name: IL1RL1 interleukin 1 receptor-like 1 [ Homo sapiens ]
Official Symbol: IL1RL1
Synonyms: IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623;
Gene ID: 9173
mRNA Refseq: NM_003856
Protein Refseq: NP_003847
MIM: 601203
UniProt ID: Q01638
Chromosome Location: 2q12
Function: cytokine receptor activity; interleukin-1 receptor activity; interleukin-33 binding; protein binding; receptor activity; receptor signaling protein activity;

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