"P4HA1" Related Products


Recombinant Human P4HA1, MYC/DDK-tagged

Cat.No.: P4HA1-3055TH
Product Overview: Recombinant Human P4HA1 fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
Description: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Source: HEK293 Cells
Species: Human
Molecular Mass: 59 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage: Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: P4HA1 prolyl 4-hydroxylase, alpha polypeptide I [ Homo sapiens(human) ]
Official Symbol: P4HA1
Synonyms: P4HA1; P4HA1; prolyl 4-hydroxylase, alpha polypeptide I; prolyl 4-hydroxylase subunit alpha-1; C-P4Halpha(I); collagen prolyl 4-hydroxylase alpha(I); procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; EC
Gene ID: 5033
mRNA Refseq: NM_000917
Protein Refseq: NP_000908
MIM: 176710
UniProt ID: P13674
Chromosome Location: 10q21.3-q23.1
Pathway: Arginine and proline metabolism
Function: L-ascorbic acid binding; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

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