Recombinant Human MTHFD1L, His-tagged

• Cat.No.: MTHFD1L-1082H
• Product Overview: Recombinant Human MTHFD1L protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-349
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like [ Homo sapiens ]
• Official Symbol: MTHFD1L
• Synonyms: MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; formyltetrahydrofolate synthetase domain containing 1 , FTHFSDC1; monofunctional C1-tetrahydrofolate synthase, mitochondrial; 10 formyl THF synthetase; DKFZP586G1517; FLJ21145; mitochondrial C1 tetrahydrofolate synthase; monofunctional C1 tetrahydrofolate synthase; mitochondrial; 10-formyl-THF synthetase; formyltetrahydrofolate synthetase domain containing 1; FTHFSDC1; MTC1THFS; dJ292B18.2; RP1-292B18.2; DKFZp586G1517
• Gene ID: 25902
• mRNA Refseq: NM_001242767
• Protein Refseq: NP_001229696
• MIM: 611427
• UniProt ID: Q6UB35
• Chromosome Location: 6q25.1
• Pathway: C1-unit interconversion, eukaryotes, organism-specific biosystem; C1-unit interconversion, eukaryotes, conserved biosystem; Metabolic pathways, organism-specific biosystem; One Carbon Metabolism, organism-specific biosystem; One carbon pool by folate, organism-specific biosystem; One carbon pool by folate, conserved biosystem
• Function: ATP binding; ATP binding; catalytic activity; formate-tetrahydrofolate ligase activity; formate-tetrahydrofolate ligase activity; ligase activity; methylenetetrahydrofolate dehydrogenase (NADP+) activity; nucleotide binding; protein homodimerization activ